November 21, 2005

AN INTRODUCTION TO THE MEDOCTOR SYSTEM

By Charles W. Kelly

Medoctor is the world’s first user-initiated automated health assessment / diagnostic system that can, not only, perform a differential diagnosis (DDX) of virtually all primary care diseases and conditions, but, also create an electronic health record (EHR) for each user. The patent-pending technology is owned by Medoctor, Inc. a Delaware, USA, corporation. The website address is www.medoctor.com .

The system is user-friendly and designed to allow individuals or, in some cases, semi-skilled medical assistants, to enter a maximum of data into a PC, upstream from the general practitioner, and to record that data for future use. The system works with artificial intelligence and emulates the operations of the receptionist, the physician, the medical transcriptionist and other professionals. There are four basic steps:

1. The user logs onto medoctor.com on a PC from home, office or pharmacy

2. The user enrolls and enters his vitals

3. The user checks off some diseases or conditions, creating a medical history

4. Thereafter, the system will load and an interview will start. The user needs only to answer Yes or No or Skip to a series of questions until a result appears.

The Medoctor interview differs from every other approach to automated health screening because it starts with the two basic questions that any primary care physician would ask, namely, the Onset Question - “How long have you had the problem?” and the Location Question -“Where does it hurt?”

From this point of departure, the system presents a series of questions in layman’s language that progress toward a differential diagnosis (DDX) that will show the top three probable diseases or conditions. Over one billion calculations may be performed in order to arrive at the result. The 90%+ accuracy of the Medoctor system stems from the amount of information being processed, for example, Medoctor interviews will average over 50 questions, which are far more than the human doctor has time to ask.

Once the result shows on the computer monitor, the user should click on Save, thus, creating a personal, secure, transportable electronic health record (EHR) for the user and his/ her physician. A printout will show all pertinent data including the patient history, the differential diagnosis, plus all the positive and negative questions, can be delivered to the physician for review - prior to the MD seeing the patient. This method can save every family physician considerable time and improve diagnostic accuracy.

One of the principle benefits of the Medoctor system to healthcare organizations is cost saving through early detection. Early Detection = Cost Containment.

Today, Version 2.1 of the Medoctor system is deployed on the Internet and is operational in English, Spanish, French, German and Italian. The five languages are interchangeable. A Latino, for example, can do a Medoctor health assessment in Spanish and print the results instantly in English for an American physician.

Medoctor Version 2.1 contains 830 diseases and conditions that can be diagnosed from symptoms or easy signs, including HIV infection and Depression. The company expects to soon include Avian Influenza (Bird Flu) in the database and to make the system available on cell phones as quickly as possible, to be in advance of any pandemic.

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The Medoctor system also provides a free-text area for a physician to enter information into the patient’s electronic health record, such as, confirmation of the diagnosis, recommended treatment and pharmaceuticals prescribed.

Should the user or a physician wish more information on any disease, hyperlinks are provided on the results page to the Mayo Clinic, Medlineplus and other useful resources and libraries, simply by clicking on the disease indicated on the result page.

Data collection is one of the most important elements of the Medoctor system. Today, Medoctor is probably the world’s largest repository of medical symptoms. In the future, these databases will be a valuable asset for mining by research organizations, pharmaceutical companies, insurance companies, universities and others.

A.J. Schmitt, the Chief Systems Architect of Medoctor and one of the world’s foremost computer scientists, has built an engine that will handle processing of health data more efficiently than anything on the market today. AJ supervised a team of two-dozen medical researchers to develop symptomotology that is unparalleled. AJ’s team spent two years building propriety databases from reliable medical resources and every symptom mentioned in a Medoctor interview can be traced to top medical evidence.

Medoctor had access to two very important studies in its research. One, a local study of 26,568 visits to six family physicians in California over a two-year period,

was compared to an annual Ambulatory Care Study of the CDC, made up of 20,760 “reasons for visit” to US physicians nationwide.

The company was able to identify and codify all diseases into four classes:

Class A diseases – 40 diseases represent 74% of USA primary care visits.

Class B diseases – 160 diseases make up 20% of primary care visits.

Class C diseases – 500 +/- diseases and conditions make up just under 6%.

Class D diseases are those with less than 1 diagnosis per 20,000 encounters.

Version 2.1 of the Medoctor system includes nearly all the A, B and C diseases, some of the Class D and tropical diseases and the recently popularized bioterrorist diseases. The company’s main database includes nearly 2,500 diseases for inclusion in future versions.

The company feels it is far ahead of any competition. For example, WebMD has only a rudimentary triage system and Relayhealth, which is considerably more expensive, may require multiple emails between the patient and physician to arrive at a diagnosis.

To our knowledge, Medoctor is the only system able to perform a differential diagnosis.

Security of EHRs and other data is of prime importance. The company commissioned an independent study on Privacy and Security Risk Assessment by Pricewaterhouse Coopers. Every precaution has been taken to protect the data with the use of sophisticated firewalls and other security measures.

The company is cooperating with two UN agencies, the World Health Organization (WHO) and the International Telecommunication Union (ITU) in Geneva, and is a member of the ITU Telemedicine Study Group. In October 2005, Medoctor was selected as the E-health component for a pilot project at an ITU sponsored telecentre in Zambia. The system has been demonstrated at a number of telemedicine conferences, including Luxemburg, Geneva and Cape Town.

Medoctor, Inc. has patents pending on its intellectual property at both the US Patent and Trade Office (USPTO) and the European Patent Office (EPO).

ã Medoctor, Inc. November 2005